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| Product Name: |
Genistein
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| Specifications |
HPLC |
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Genistein has been found to have a number of antioxidant activities. It is a scavenger of reactive oxygen species and inhibits lipid peroxidation. It also inhibits superoxide anion generation by the enzyme xanthine oxidase. In addition, genistein, in animal experiments, has been found to increase the activities of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, catalase and glutathione reductase.
Several mechanisms have been proposed for genistein's putative anticarcinogenic activity. These include upregulation of apoptosis, inhibition of angiogenesis, inhibition of DNA topoisomerase II and inhibition of protein tyrosine kinases. Genistein's weak estrogenic activity has been suggested as another mechanism for genistein's putative anti-prostate cancer activity. In addition to the above mechanisms, other mechanisms of genistein's putative anti-prostate cancer activity include inhibition of nuclear factor (NF)-Kappa B in prostate cancer cells, downregulation of TGF (transforming growth factor)-beta and inhibition of EGF (epidermal growth factor)-stimulated growth. Genistein's anti-estrogenic action may be another possible mechanism to explain its putative anti-breast cancer activity. In the final analysis, the mechanism of genistein's putative anticarcinogenic activity is unclear.
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| Company: |
Xi'an Arica Botanical Product Co.,Ltd
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| Contact: |
Mr. Jason Zhao |
| Address: |
Rm.6-10302 of XinXiLan, No.209 of KeJiLu Road, Xi’an Hi-Tech Development Zone, Xi’an, China |
| Postcode: |
710065 |
| Tel: |
86 29 88362049 |
| Fax: |
86 29 88361064 |
| E-mail: |
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